With this call the Novo Nordisk Foundation seeks to support and strengthen the development of young and promising research leaders, and to promote Nordic research at a high international level. The call is targeted starting group leaders with ambitious projects within endocrinology and metabolism that aim to understand the human organism and the mechanisms underlying health and disease at a basic and clinical level. Four grants are available for funding and NNF aims at awarding at least one of these grants to an active clinician researcher.